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sip-1 Stress-induced protein 1 [ Caenorhabditis elegans ]

Gene ID: 176471, updated on 2-Nov-2024

Summary

Official Symbol
sip-1
Official Full Name
Stress-induced protein 1
Primary source
WormBase:WBGene00004798
Locus tag
CELE_F43D9.4
See related
AllianceGenome:WB:WBGene00004798
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable unfolded protein binding activity. Involved in determination of adult lifespan; embryo development; and response to heat. Located in cytosol. Is expressed in body wall musculature; gonad; and intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See sip-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003281.10 (10506106..10506801, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene TAFII28-like protein domain-containing protein Neighboring gene Ubiquitin-related modifier 1 homolog Neighboring gene ncRNA Neighboring gene Sec1 family domain-containing protein 1 Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables unfolded protein binding IC
Inferred by Curator
more info
PubMed 
Process Evidence Code Pubs
involved_in determination of adult lifespan IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in determination of adult lifespan IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein metabolic process IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in response to heat IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in response to heat IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Stress-induced protein 1
NP_499316.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10506106..10506801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066915.5NP_499316.1  Stress-induced protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499316.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q20363
    Conserved Domains (1) summary
    cd06526
    Location:45126
    metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...