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zig-5 Zwei Ig domain protein zig-5 [ Caenorhabditis elegans ]

Gene ID: 176527, updated on 2-Nov-2024

Summary

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Official Symbol
zig-5
Official Full Name
Zwei Ig domain protein zig-5
Primary source
WormBase:WBGene00006982
Locus tag
CELE_Y48A6A.1
See related
AllianceGenome:WB:WBGene00006982
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in pattern specification process. Predicted to be located in membrane. Is expressed in intestine and nervous system. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See zig-5 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (10951119..10953508, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Regulation of longevity by E3 ubiquitin-protein ligase Neighboring gene ncRNA Neighboring gene STE20-related kinase adapter protein strd-1 Neighboring gene BPTI/Kunitz inhibitor domain-containing protein Neighboring gene tRNA-Arg Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The secreted immunoglobulin domain proteins ZIG-5 and ZIG-8 cooperate with L1CAM/SAX-7 to maintain nervous system integrity. Bénard CY, et al. PLoS Genet, 2012. PMID 22829780, Free PMC Article
  2. Identification of spatial and temporal cues that regulate postembryonic expression of axon maintenance factors in the C. elegans ventral nerve cord. Aurelio O, et al. Development, 2003 Feb. PMID 12490565
  3. Immunoglobulin-domain proteins required for maintenance of ventral nerve cord organization. Aurelio O, et al. Science, 2002 Jan 25. PMID 11809975
  4. The small, secreted immunoglobulin protein ZIG-3 maintains axon position in Caenorhabditis elegans. Bénard C, et al. Genetics, 2009 Nov. PMID 19737747, Free PMC Article
  5. The immunoglobulin superfamily in Caenorhabditis elegans and Drosophila melanogaster. Hobert O, et al. Development, 2004 May. PMID 15128663

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in pattern specification process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Zwei Ig domain protein zig-5
NP_499405.4
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10951119..10953508 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067004.7 → NP_499405.4  Zwei Ig domain protein zig-5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499405.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8WR47, Q9XXD7
    Conserved Domains (2) summary
    cd00096
    Location:62 → 131
    Ig; Immunoglobulin domain
    cl11960
    Location:185 → 249
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XXD7.2

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