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Y47D3A.14 CMP/dCMP-type deaminase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176551, updated on 2-Nov-2024

Summary

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Official Symbol
Y47D3A.14
Official Full Name
CMP/dCMP-type deaminase domain-containing protein
Primary source
WormBase:WBGene00012927
Locus tag
CELE_Y47D3A.14
See related
AllianceGenome:WB:WBGene00012927
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable catalytic activity. Predicted to contribute to tRNA-specific adenosine-34 deaminase activity. Predicted to be active in cytoplasm and nucleus. Is expressed in pharyngeal gland cell and pm7. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies. Orthologous to human ADAT3 (adenosine deaminase tRNA specific 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y47D3A.14 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (11235581..11236868, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Elongation of very long chain fatty acids protein;Very-long-chain 3-oxoacyl-CoA synthase Neighboring gene AcidPPc domain-containing protein Neighboring gene Association with the SNF1 complex (ASC) domain-containing protein Neighboring gene ncRNA Neighboring gene Ribosomal protein S6 kinase beta

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to tRNA-specific adenosine-34 deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
CMP/dCMP-type deaminase domain-containing protein
NP_499445.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    11235581..11236868 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067044.5 → NP_499445.2  CMP/dCMP-type deaminase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499445.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NAH8
    Conserved Domains (1) summary
    cd01285
    Location:164 → 251
    nucleoside_deaminase; Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a ...
Nucleotide Protein
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