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aakb-2 Association with the SNF1 complex (ASC) domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176552, updated on 2-Nov-2024

Summary

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Official Symbol
aakb-2
Official Full Name
Association with the SNF1 complex (ASC) domain-containing protein
Primary source
WormBase:WBGene00012928
Locus tag
CELE_Y47D3A.15
See related
AllianceGenome:WB:WBGene00012928
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. Predicted to be part of nucleotide-activated protein kinase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human PRKAB1 (protein kinase AMP-activated non-catalytic subunit beta 1) and PRKAB2 (protein kinase AMP-activated non-catalytic subunit beta 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See aakb-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003281.10 (11237143..11239204)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene AcidPPc domain-containing protein Neighboring gene CMP/dCMP-type deaminase domain-containing protein Neighboring gene ncRNA Neighboring gene Ribosomal protein S6 kinase beta Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Differential requirements for STRAD in LKB1-dependent functions in C. elegans. Narbonne P, et al. Development, 2010 Feb. PMID 20110331
  2. Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Narbonne P, et al. Nature, 2009 Jan 8. PMID 19052547
  3. Caenorhabditis elegans as a screening tool for the endothelial cell-derived putative aging-related proteins detected by proteomic analysis. Ha MK, et al. Proteomics, 2006 Jun. PMID 16673436
  4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of nucleotide-activated protein kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Association with the SNF1 complex (ASC) domain-containing protein
NP_499446.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    11237143..11239204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067045.3 → NP_499446.1  Association with the SNF1 complex (ASC) domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499446.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NAH7
    Conserved Domains (2) summary
    smart01010
    Location:190 → 274
    AMPKBI; 5'-AMP-activated protein kinase beta subunit, interation domain
    pfam16561
    Location:62 → 147
    AMPK1_CBM; Glycogen recognition site of AMP-activated protein kinase
Nucleotide Protein
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