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Y66D12A.8 STING ER exit protein [ Caenorhabditis elegans ]

Gene ID: 176589, updated on 2-Nov-2024

Summary

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Official Symbol
Y66D12A.8
Official Full Name
STING ER exit protein
Primary source
WormBase:WBGene00013434
Locus tag
CELE_Y66D12A.8
See related
AllianceGenome:WB:WBGene00013434
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 107. Orthologous to human STEEP1 (STING1 ER exit protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y66D12A.8 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003281.10 (11574221..11578719)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene MITD1 C-terminal phospholipase D-like domain-containing protein Neighboring gene Proteasome activator PA28 C-terminal domain-containing protein;Proteasome activator complex subunit 3 Neighboring gene Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article
  2. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
  3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in endoplasmic reticulum membrane organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
STING ER exit protein
NP_001255130.2
  • Partially confirmed by transcript evidence
NP_001255131.2
  • Partially confirmed by transcript evidence
NP_001255132.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    11574221..11578719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268201.5 → NP_001255130.2  STING ER exit protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255130.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95Q06

  2. NM_001268202.5 → NP_001255131.2  STING ER exit protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255131.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2HK16

  3. NM_001268203.3 → NP_001255132.1  STING ER exit protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255132.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2HK17
Nucleotide Protein
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