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epc-1 Enhancer of polycomb-like protein [ Caenorhabditis elegans ]

Gene ID: 176679, updated on 2-Nov-2024

Summary

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Official Symbol
epc-1
Official Full Name
Enhancer of polycomb-like protein
Primary source
WormBase:WBGene00007030
Locus tag
CELE_Y111B2A.11
See related
AllianceGenome:WB:WBGene00007030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of piccolo histone acetyltransferase complex. Is expressed in several structures, including body wall musculature; intestine; pharynx; tail; and vulval muscle. Orthologous to several human genes including EPC1 (enhancer of polycomb homolog 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See epc-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
9
Sequence:
Chromosome: III; NC_003281.10 (12599630..12608467, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene CBS domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA Neighboring gene WD_REPEATS_REGION domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A chromodomain protein mediates heterochromatin-directed piRNA expression. Huang X, et al. Proc Natl Acad Sci U S A, 2021 Jul 6. PMID 34187893, Free PMC Article
  2. A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling. Ceol CJ, et al. Dev Cell, 2004 Apr. PMID 15068795
  3. The Caenorhabditis elegans ekl (enhancer of ksr-1 lethality) genes include putative components of a germline small RNA pathway. Rocheleau CE, et al. Genetics, 2008 Mar. PMID 18245826, Free PMC Article
  4. The PLZF-like protein TRA-4 cooperates with the Gli-like transcription factor TRA-1 to promote female development in C. elegans. Grote P, et al. Dev Cell, 2006 Oct. PMID 17011494
  5. Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans. Poulin G, et al. EMBO J, 2005 Jul 20. PMID 15990876, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
  
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of NuA4 histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of piccolo histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Enhancer of polycomb-like protein
NP_001370109.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    12599630..12608467 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383013.2 → NP_001370109.1  Enhancer of polycomb-like protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EC14
    Conserved Domains (1) summary
    pfam10513
    Location:9 → 131
    EPL1; Enhancer of polycomb-like
Nucleotide Protein
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