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cec-7 Chromo domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176704, updated on 2-Nov-2024

Summary

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Official Symbol
cec-7
Official Full Name
Chromo domain-containing protein
Primary source
WormBase:WBGene00012551
Locus tag
CELE_Y37D8A.11
See related
AllianceGenome:WB:WBGene00012551
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in chromatin organization and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Orthologous to human MORF4L1 (mortality factor 4 like 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cec-7 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (12875783..12877577, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Mortality factor related protein 1 Neighboring gene Signal peptidase complex subunit 2 Neighboring gene ENhancer of Uncoordination Neighboring gene Disintegrin and metalloproteinase domain-containing protein unc-71 Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional analysis of MRG-1: the ortholog of human MRG15 in Caenorhabditis elegans. Olgun A, et al. J Gerontol A Biol Sci Med Sci, 2005 May. PMID 15972600
  2. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
  3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Chromo domain-containing protein
NP_001022827.1
  • Confirmed by transcript evidence
NP_001022828.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    12875783..12877577 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027656.7 → NP_001022827.1  Chromo domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022827.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XWW0
    Conserved Domains (2) summary
    smart00298
    Location:344 → 374
    CHROMO; Chromatin organization modifier domain
    pfam11717
    Location:427 → 476
    Tudor-knot; RNA binding activity-knot of a chromodomain

  2. NM_001027657.3 → NP_001022828.1  Chromo domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022828.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q69Z09
    Conserved Domains (2) summary
    smart00298
    Location:251 → 281
    CHROMO; Chromatin organization modifier domain
    pfam11717
    Location:334 → 383
    Tudor-knot; RNA binding activity-knot of a chromodomain
Nucleotide Protein
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