pgm-2 PGM_PMM_I domain-containing protein;Phosphoglucomutase-2 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: pgm-2
Official Full Name: PGM_PMM_I domain-containing protein;Phosphoglucomutase-2
Primary source: WormBase:WBGene00012803
Locus tag: CELE_Y43F4B.5
See related: AllianceGenome:WB:WBGene00012803
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable phosphopentomutase activity. Predicted to be involved in purine ribonucleoside salvage. Located in nucleus. Orthologous to human PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2 like 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pgm-2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (13299378..13302760)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y43F4B.5 (e-PCR)
- UniSTS:311191

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables intramolecular phosphotransferase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphopentomutase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in purine ribonucleoside salvage	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	HDA more info	PubMed

General protein information

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Preferred Names: PGM_PMM_I domain-containing protein;Phosphoglucomutase-2

NP_001022872.1

Confirmed by transcript evidence

NP_001022873.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

13299378..13302760

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001027701.5 → NP_001022872.1 Phosphoglucomutase-2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022872.1

Status: REVIEWED

UniProtKB/TrEMBL

O45934

Conserved Domains (2) summary

cd05799
Location:47 → 574

PGM2; This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and ...

PTZ00150
Location:7 → 595

PTZ00150; phosphoglucomutase-2-like protein; Provisional
NM_001027702.5 → NP_001022873.1 PGM_PMM_I domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022873.1

Status: REVIEWED

UniProtKB/TrEMBL

Q86DA0

Conserved Domains (1) summary

cl03757
Location:47 → 323

phosphohexomutase; The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine ...