ears-2 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial [Caenorhabditis elegans] - Gene

Summary

Official Symbol: ears-2
Official Full Name: Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial
Primary source: WormBase:WBGene00001338
Locus tag: CELE_T07A9.2
See related: AllianceGenome:WB:WBGene00001338
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable glutamate-tRNA ligase activity. Predicted to be involved in glutamyl-tRNA aminoacylation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 12. Orthologous to human EARS2 (glutamyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables aminoacyl-tRNA ligase activity	IEA Inferred from Electronic Annotation more info
enables glutamate-tRNA ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutamate-tRNA ligase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables tRNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glutamyl-tRNA aminoacylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in glutamyl-tRNA aminoacylation	IEA Inferred from Electronic Annotation more info
involved_in tRNA aminoacylation	IEA Inferred from Electronic Annotation more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

Preferred Names: Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

NP_499917.2

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The following sections contain reference sequences that belong to a specific genome build. Explain