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trap-3 Translocon-associated protein subunit gamma [ Caenorhabditis elegans ]

Gene ID: 177028, updated on 2-Nov-2024

Summary

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Official Symbol
trap-3
Official Full Name
Translocon-associated protein subunit gamma
Primary source
WormBase:WBGene00021420
Locus tag
CELE_Y38F2AR.2
See related
AllianceGenome:WB:WBGene00021420
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SSR3 (signal sequence receptor subunit 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See trap-3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (2389445..2390259)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Protein transport protein Sec61 subunit beta Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein;Tudor domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular basis of the TRAP complex function in ER protein biogenesis. Jaskolowski M, et al. Nat Struct Mol Biol, 2023 Jun. PMID 37170030, Free PMC Article
  2. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article
  3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Translocon-associated protein subunit gamma
NP_500198.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    2389445..2390259
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067797.8 → NP_500198.1  Translocon-associated protein subunit gamma [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500198.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95XS1
    Conserved Domains (1) summary
    pfam07074
    Location:7 → 176
    TRAP-gamma; Translocon-associated protein, gamma subunit (TRAP-gamma)
Nucleotide Protein
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