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Y69A2AR.19 Protein-tyrosine-phosphatase [ Caenorhabditis elegans ]

Gene ID: 177036, updated on 2-Nov-2024

Summary

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Official Symbol
Y69A2AR.19
Official Full Name
Protein-tyrosine-phosphatase
Primary source
WormBase:WBGene00022090
Locus tag
CELE_Y69A2AR.19
See related
AllianceGenome:WB:WBGene00022090
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y69A2AR.19 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
11
Sequence:
Chromosome: IV; NC_003282.8 (2488820..2494186)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Phospholipase A2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Coiled-coil domain-containing protein 12

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein-tyrosine-phosphatase
NP_001294610.1
  • Confirmed by transcript evidence
NP_001360613.1
  • Confirmed by transcript evidence
NP_500211.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    2488820..2494186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067810.5 → NP_500211.3  Protein-tyrosine-phosphatase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500211.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95XJ2
    Conserved Domains (3) summary
    cd00047
    Location:1019 → 1245
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00102
    Location:1018 → 1245
    Y_phosphatase; Protein-tyrosine phosphatase
    pfam02206
    Location:172 → 234
    WSN; Domain of unknown function

  2. NM_001307681.3 → NP_001294610.1  Protein-tyrosine-phosphatase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294610.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PMU1
    Conserved Domains (3) summary
    cd00047
    Location:1012 → 1238
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00102
    Location:1011 → 1238
    Y_phosphatase; Protein-tyrosine phosphatase
    pfam02206
    Location:165 → 227
    WSN; Domain of unknown function

  3. NM_001372744.2 → NP_001360613.1  Protein-tyrosine-phosphatase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IL30
    Conserved Domains (3) summary
    TIGR01612
    Location:382 → 762
    235kDa-fam; reticulocyte binding/rhoptry protein
    smart00194
    Location:928 → 1161
    PTPc; Protein tyrosine phosphatase, catalytic domain
    pfam02206
    Location:92 → 154
    WSN; Domain of unknown function
Nucleotide Protein
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