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zip-11 Transcription factor zip-11 [ Caenorhabditis elegans ]

Gene ID: 177099, updated on 2-Nov-2024

Summary

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Official Symbol
zip-11
Official Full Name
Transcription factor zip-11
Primary source
WormBase:WBGene00021082
Locus tag
CELE_W08E12.1
See related
AllianceGenome:WB:WBGene00021082
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables DNA-binding transcription factor binding activity. Involved in defense response to Gram-negative bacterium. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See zip-11 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (3311276..3313189)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Chorion class high-cysteine HCB protein 12-like Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The bZIP Transcription Factor ZIP-11 Is Required for the Innate Immune Regulation in Caenorhabditis elegans. Zheng Z, et al. Front Immunol, 2021. PMID 34804026, Free PMC Article
  2. Co-regulation by Notch and Fos is required for cell fate specification of intermediate precursors during C. elegans uterine development. Oommen KS, et al. Development, 2007 Nov. PMID 17942488
  3. H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity. Methot SP, et al. Nat Cell Biol, 2021 Nov. PMID 34737442, Free PMC Article
  4. Networks of bZIP protein-protein interactions diversified over a billion years of evolution. Reinke AW, et al. Science, 2013 May 10. PMID 23661758, Free PMC Article
  5. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Transcription factor zip-11
NP_500318.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    3311276..3313189
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067917.6 → NP_500318.1  Transcription factor zip-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500318.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9N5A8
    Conserved Domains (1) summary
    cd14692
    Location:166 → 224
    bZIP_ATF4; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-4 (ATF-4) and similar proteins: a DNA-binding and dimerization domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N5A8.1

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