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clec-67 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177151, updated on 2-Nov-2024

Summary

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Official Symbol
clec-67
Official Full Name
C-type lectin domain-containing protein
Primary source
WormBase:WBGene00018971
Locus tag
CELE_F56D6.2
See related
AllianceGenome:WB:WBGene00018971
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in PERK-mediated unfolded protein response. Is expressed in intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See clec-67 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
9
Sequence:
Chromosome: IV; NC_003282.8 (3922165..3924515)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Transmembrane protein Neighboring gene Serpentine Receptor, class Z Neighboring gene C-type lectin domain-containing protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Parkinson's disease-associated DJ-1 modulates innate immunity signaling in Caenorhabditis elegans. Cornejo Castro EM, et al. J Neural Transm (Vienna), 2010 May. PMID 20376509
  2. Innate immune genes including a mucin-like gene, mul-1, induced by ionizing radiation in Caenorhabditis elegans. Kimura T, et al. Radiat Res, 2012 Oct. PMID 22967128
  3. Modulatory upregulation of an insulin peptide gene by different pathogens in C. elegans. Lee SH, et al. Virulence, 2018 Dec 31. PMID 29405821, Free PMC Article
  4. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. Lo Sasso G, et al. PLoS One, 2014. PMID 25013930, Free PMC Article
  5. A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Reddy KC, et al. Science, 2009 Jan 16. PMID 19150845, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in PERK-mediated unfolded protein response HEP PubMed 

General protein information

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Preferred Names
C-type lectin domain-containing protein
NP_500437.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    3922165..3924515
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068036.7 → NP_500437.2  C-type lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500437.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8ITX4
    Conserved Domains (1) summary
    pfam00059
    Location:39 → 145
    Lectin_C; Lectin C-type domain
Nucleotide Protein
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