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puf-7 Pumilio domain-containing protein 7 [ Caenorhabditis elegans ]

Gene ID: 177332, updated on 2-Nov-2024

Summary

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Official Symbol
puf-7
Official Full Name
Pumilio domain-containing protein 7
Primary source
WormBase:WBGene00004243
Locus tag
CELE_B0273.2
See related
AllianceGenome:WB:WBGene00004243
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable mRNA 3'-UTR binding activity. Involved in germ cell development. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See puf-7 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (5486713..5490322)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene IMV membrane protein Neighboring gene snRNA-activating protein complex subunit 3 Neighboring gene Chitotriosidase-1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The RNA-binding proteins PUF-5, PUF-6, and PUF-7 reveal multiple systems for maternal mRNA regulation during C. elegans oogenesis. Lublin AL, et al. Dev Biol, 2007 Mar 15. PMID 17234175
  2. Characteristics and evolution of the PUF gene family in Bombyx mori and 27 other species. Zhang CD, et al. Mol Biol Rep, 2012 Jan. PMID 21598114
  3. A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity. Stumpf CR, et al. RNA, 2008 Aug. PMID 18579869, Free PMC Article
  4. nos-1 and nos-2, two genes related to Drosophila nanos, regulate primordial germ cell development and survival in Caenorhabditis elegans. Subramaniam K, et al. Development, 1999 Nov. PMID 10518502
  5. The Caenorhabditis elegans pumilio homolog, puf-9, is required for the 3'UTR-mediated repression of the let-7 microRNA target gene, hbl-1. Nolde MJ, et al. Dev Biol, 2007 May 15. PMID 17412319, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in germ cell development IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in oogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in post-transcriptional regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Pumilio domain-containing protein 7
NP_500820.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    5486713..5490322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068419.7 → NP_500820.1  Pumilio domain-containing protein 7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500820.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O44169
    Conserved Domains (1) summary
    cl21719
    Location:82 → 449
    Pumilio; Pumilio-family RNA binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O44169.1

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