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csn-5 COP9 signalosome complex subunit 5 [ Caenorhabditis elegans ]

Gene ID: 177342, updated on 2-Nov-2024

Summary

Official Symbol
csn-5
Official Full Name
COP9 signalosome complex subunit 5
Primary source
WormBase:WBGene00000817
Locus tag
CELE_B0547.1
See related
AllianceGenome:WB:WBGene00000817
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables DEAD/H-box RNA helicase binding activity. Involved in gonad development; oogenesis; and protein deneddylation. Located in A band and nucleus. Is expressed in body wall musculature; intestine; pharynx; reproductive system; and tail. Orthologous to human COPS5 (COP9 signalosome subunit 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See csn-5 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (5649533..5651079)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene BZIP domain-containing protein;Protein skinhead-1 Neighboring gene C-type lectin domain-containing protein Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DEAD/H-box RNA helicase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables deNEDDylase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metallopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in oogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in oogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein deneddylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein deneddylation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
involved_in reproductive process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in A band IDA
Inferred from Direct Assay
more info
PubMed 
part_of COP9 signalosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of COP9 signalosome IEA
Inferred from Electronic Annotation
more info
 
part_of COP9 signalosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
COP9 signalosome complex subunit 5
NP_500841.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    5649533..5651079
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068440.5NP_500841.1  COP9 signalosome complex subunit 5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500841.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91001
    Conserved Domains (1) summary
    cd08069
    Location:45292
    MPN_RPN11_CSN5; Mov34/MPN/PAD-1 family: proteasomal regulatory protein Rpn11 and signalosome complex subunit CSN5