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nhr-46 Nuclear Hormone Receptor family [ Caenorhabditis elegans ]

Gene ID: 177350, updated on 2-Nov-2024

Summary

Official Symbol
nhr-46
Official Full Name
Nuclear Hormone Receptor family
Primary source
WormBase:WBGene00003636
Locus tag
CELE_C45E5.6
See related
AllianceGenome:WB:WBGene00003636
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in hypodermis; intestine; muscle cell; neurons; and reproductive system. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See nhr-46 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (5747363..5757862, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Glycerol-3-phosphate phosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Nuclear Hormone Receptor family
NP_001023065.1
  • Product from WormBase gene class nhr;
    Confirmed by transcript evidence
NP_001367663.1
  • Product from WormBase gene class nhr;
    Confirmed by transcript evidence
NP_500858.2
  • Product from WormBase gene class nhr;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    5747363..5757862 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068457.6NP_500858.2  Nuclear Hormone Receptor family [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500858.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZB8, Q9GTH2
    Conserved Domains (2) summary
    cd06157
    Location:317492
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
    smart00399
    Location:98167
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
  2. NM_001027894.8NP_001023065.1  Nuclear Hormone Receptor family [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023065.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95QR2
    Conserved Domains (2) summary
    cd06157
    Location:365540
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
    smart00399
    Location:146215
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
  3. NM_001380240.1NP_001367663.1  Nuclear Hormone Receptor family [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95QR3
    Conserved Domains (2) summary
    cd06157
    Location:184359
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
    cl02596
    Location:248
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers