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inx-7 Innexin;Innexin-7 [ Caenorhabditis elegans ]

Gene ID: 177364, updated on 2-Nov-2024

Summary

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Official Symbol
inx-7
Official Full Name
Innexin;Innexin-7
Primary source
WormBase:WBGene00002129
Locus tag
CELE_K02B2.4
See related
AllianceGenome:WB:WBGene00002129
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in gap junction and plasma membrane. Is expressed in neurons; pharyngeal cell; and rectal gland cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See inx-7 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (5943981..5946638, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Cat eye syndrome critical region protein 5;Host attachment protein Neighboring gene Calcium uniporter protein, mitochondrial Neighboring gene Fructose-2,6-bisphosphatase Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein eS25 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Presynaptic coupling by electrical synapses coordinates a rhythmic behavior by synchronizing the activities of a neuron pair. Choi U, et al. Proc Natl Acad Sci U S A, 2021 May 18. PMID 33972428, Free PMC Article
  2. The Caenorhabditis elegans avermectin resistance and anesthetic response gene unc-9 encodes a member of a protein family implicated in electrical coupling of excitable cells. Barnes TM, et al. J Neurochem, 1997 Dec. PMID 9375655
  3. The role of gap junctions in Caenorhabditis elegans oocyte maturation and fertilization. Whitten SJ, et al. Dev Biol, 2007 Jan 15. PMID 16982048
  4. The head mesodermal cell couples FMRFamide neuropeptide signaling with rhythmic muscle contraction in C. elegans. Choi U, et al. Nat Commun, 2023 Jul 14. PMID 37452027, Free PMC Article
  5. Locomotion modulates olfactory learning through proprioception in C. elegans. Zhan X, et al. Nat Commun, 2023 Jul 27. PMID 37500635, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gap junction channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables gap junction hemi-channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in gap junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in gap junction IEA
Inferred from Electronic Annotation
more info
  
located_in gap junction ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Innexin;Innexin-7
NP_001293767.1
  • Confirmed by transcript evidence
NP_500894.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    5943981..5946638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068493.8 → NP_500894.1  Innexin-7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500894.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21123
    Conserved Domains (1) summary
    pfam00876
    Location:20 → 407
    Innexin; Innexin

  2. NM_001306838.3 → NP_001293767.1  Innexin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293767.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLI7
    Conserved Domains (1) summary
    pfam00876
    Location:9 → 164
    Innexin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q21123.1

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