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nstp-2 UDP-xylose and UDP-N-acetylglucosamine transporter [ Caenorhabditis elegans ]

Gene ID: 177424, updated on 2-Nov-2024

Summary

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Official Symbol
nstp-2
Official Full Name
UDP-xylose and UDP-N-acetylglucosamine transporter
Primary source
WormBase:WBGene00017480
Locus tag
CELE_F15B10.1
See related
AllianceGenome:WB:WBGene00017480
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable UDP-N-acetylglucosamine transmembrane transporter activity and UDP-xylose transmembrane transporter activity. Predicted to be involved in UDP-N-acetylglucosamine transmembrane transport. Predicted to be located in endomembrane system and membrane. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Is expressed in hypodermis; intestine; nervous system; and pharynx. Orthologous to human SLC35B4 (solute carrier family 35 member B4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nstp-2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (6603998..6606188, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene SUPpressor Neighboring gene ncRNA Neighboring gene BTB domain-containing protein Neighboring gene Helicase ATP-binding domain-containing protein;RNA helicase Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spatial single-cell sequencing of meiosis I arrested oocytes indicates acquisition of maternal transcripts from the soma. Trimmer KA, et al. Cell Rep, 2023 Jun 27. PMID 37227820, Free PMC Article
  2. Carbohydrates and glycosylation. Berninsone PM. WormBook, 2006 Dec 18. PMID 18050430, Free PMC Article
  3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables UDP-N-acetylglucosamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-xylose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in UDP-xylose transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UDP-xylose and UDP-N-acetylglucosamine transporter
NP_001040936.1
  • Confirmed by transcript evidence
NP_001370348.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    6603998..6606188 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383108.2 → NP_001370348.1  UDP-xylose and UDP-N-acetylglucosamine transporter [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q336L5
    Conserved Domains (1) summary
    pfam08449
    Location:1 → 278
    UAA; UAA transporter family

  2. NM_001047471.8 → NP_001040936.1  UDP-xylose and UDP-N-acetylglucosamine transporter [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040936.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44166
    Conserved Domains (2) summary
    pfam08449
    Location:7 → 310
    UAA; UAA transporter family
    cl23754
    Location:91 → 304
    EamA; EamA-like transporter family
Nucleotide Protein
Heading Accession and Version

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