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pitr-1 Phosphate transporter [ Caenorhabditis elegans ]

Gene ID: 177512, updated on 2-Nov-2024

Summary

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Official Symbol
pitr-1
Official Full Name
Phosphate transporter
Primary source
WormBase:WBGene00016739
Locus tag
CELE_C48A7.2
See related
AllianceGenome:WB:WBGene00016739
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Is expressed in several structures, including body wall musculature; germ line; hermaphrodite gonad; intestine; and nerve ring. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pitr-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
8
Sequence:
Chromosome: IV; NC_003282.8 (7394085..7397584)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Linking Gene Expression in the Intestine to Production of Gametes Through the Phosphate Transporter PITR-1 in Caenorhabditis elegans. Balklava Z, et al. Genetics, 2016 Sep. PMID 27449055, Free PMC Article
  2. A genome-wide map of conserved microRNA targets in C. elegans. Lall S, et al. Curr Biol, 2006 Mar 7. PMID 16458514
  3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in inorganic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphate ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphate ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Phosphate transporter
NP_001367368.1
  • Confirmed by transcript evidence
NP_001368450.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7394085..7397584
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001380320.1 → NP_001367368.1  Phosphate transporter [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18697
    Conserved Domains (1) summary
    pfam01384
    Location:24 → 503
    PHO4; Phosphate transporter family

  2. NM_001380321.1 → NP_001368450.1  Phosphate transporter [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    W6RS06
    Conserved Domains (1) summary
    pfam01384
    Location:1 → 435
    PHO4; Phosphate transporter family

RNA

  1. NR_131566.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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