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nep-16 Peptidase M13 N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177541, updated on 2-Nov-2024

Summary

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Official Symbol
nep-16
Official Full Name
Peptidase M13 N-terminal domain-containing protein
Primary source
WormBase:WBGene00018472
Locus tag
CELE_F45E4.7
See related
AllianceGenome:WB:WBGene00018472
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nep-16 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
16
Sequence:
Chromosome: IV; NC_003282.8 (7635653..7641858, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene EGF-like domain-containing protein Neighboring gene ncRNA Neighboring gene Transcriptional activator plp-1 Neighboring gene ADP-ribosylation factor 1-like 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Peptidase M13 N-terminal domain-containing protein
NP_001023203.2
  • Confirmed by transcript evidence
NP_001023205.2
  • Confirmed by transcript evidence
NP_001370406.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7635653..7641858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383127.2 → NP_001370406.1  Peptidase M13 N-terminal domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86MG1
    Conserved Domains (1) summary
    cl14813
    Location:17 → 362
    GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)

  2. NM_001028032.7 → NP_001023203.2  Peptidase M13 N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023203.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KYL1
    Conserved Domains (1) summary
    cl14813
    Location:254 → 725
    GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)

  3. NM_001028034.5 → NP_001023205.2  Peptidase M13 N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023205.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KYL2
    Conserved Domains (1) summary
    cl14813
    Location:170 → 641
    GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
Nucleotide Protein
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Gene LinkOut

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