U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nrde-4 ANK_REP_REGION domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177544, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
nrde-4
Official Full Name
ANK_REP_REGION domain-containing protein
Primary source
WormBase:WBGene00001584
Locus tag
CELE_F45E4.10
See related
AllianceGenome:WB:WBGene00001584
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See nrde-4 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
13
Sequence:
Chromosome: IV; NC_003282.8 (7646320..7654262, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene HMG box-containing protein 5 Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Activin_recp domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. lin-4 and the NRDE pathway are required to activate a transgenic lin-4 reporter but not the endogenous lin-4 locus in C. elegans. Jiao AL, et al. PLoS One, 2018. PMID 29324872, Free PMC Article
  2. Small RNAs, RNAi and the inheritance of gene silencing in Caenorhabditis elegans. Feng X, et al. J Genet Genomics, 2013 Apr 20. PMID 23618398
  3. Nuclear RNAi maintains heritable gene silencing in Caenorhabditis elegans. Burton NO, et al. Proc Natl Acad Sci U S A, 2011 Dec 6. PMID 22106253, Free PMC Article
  4. A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality. Buckley BA, et al. Nature, 2012 Sep 20. PMID 22810588, Free PMC Article
  5. A pre-mRNA-associating factor links endogenous siRNAs to chromatin regulation. Burkhart KB, et al. PLoS Genet, 2011 Aug. PMID 21901112, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in regulatory ncRNA-mediated post-transcriptional gene silencing IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
ANK_REP_REGION domain-containing protein
NP_001343615.1
  • Confirmed by transcript evidence
NP_001343616.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7646320..7654262 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356928.3 → NP_001343615.1  ANK_REP_REGION domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9BI64

  2. NM_001356927.2 → NP_001343616.1  ANK_REP_REGION domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KYL3
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools