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pcp-3 Peptidase S28 [ Caenorhabditis elegans ]

Gene ID: 177740, updated on 2-Nov-2024

Summary

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Official Symbol
pcp-3
Official Full Name
Peptidase S28
Primary source
WormBase:WBGene00003958
Locus tag
CELE_F23B2.11
See related
AllianceGenome:WB:WBGene00003958
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Orthologous to human PRSS16 (serine protease 16). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pcp-3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (9155148..9159019, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene RING-type domain-containing protein Neighboring gene ncRNA Neighboring gene Peptidase S28

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans. Pinkston-Gosse J, et al. Nat Genet, 2007 Nov. PMID 17934462
  2. An analysis of the Caenorhabditis elegans lipid raft proteome using geLC-MS/MS. Rao W, et al. J Proteomics, 2011 Feb 1. PMID 21070894
  3. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
  4. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables dipeptidyl-peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type exopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane raft HDA PubMed 

General protein information

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Preferred Names
Peptidase S28
NP_001366906.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    9155148..9159019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001380398.3 → NP_001366906.1  Peptidase S28 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O02252
    Conserved Domains (2) summary
    pfam05577
    Location:583 → 1013
    Peptidase_S28; Serine carboxypeptidase S28
    cl21494
    Location:50 → 478
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
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