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ent-7 Equilibrative Nucleoside Transporter (ENT) Family [ Caenorhabditis elegans ]

Gene ID: 177862, updated on 2-Nov-2024

Summary

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Official Symbol
ent-7
Official Full Name
Equilibrative Nucleoside Transporter (ENT) Family
Primary source
WormBase:WBGene00009686
Locus tag
CELE_F44D12.9
See related
AllianceGenome:WB:WBGene00009686
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Orthologous to several human genes including SLC29A3 (solute carrier family 29 member 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ent-7 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
10
Sequence:
Chromosome: IV; NC_003282.8 (10017425..10021290)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene PDZ domain-containing protein Neighboring gene DUF281 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Phosphotriesterase-related protein Neighboring gene MSP domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
  2. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables nucleoside transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleoside transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in nucleoside transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleoside transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Equilibrative Nucleoside Transporter (ENT) Family
NP_001255452.1
  • Confirmed by transcript evidence
NP_001367263.1
  • Confirmed by transcript evidence
NP_001379100.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10017425..10021290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001380428.1 → NP_001367263.1  Equilibrative Nucleoside Transporter (ENT) Family [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1B6S1
    Conserved Domains (1) summary
    cl15430
    Location:56 → 439
    Nucleoside_tran; Nucleoside transporter

  2. NM_001392380.1 → NP_001379100.1  Equilibrative Nucleoside Transporter (ENT) Family [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20396
    Conserved Domains (1) summary
    cl15430
    Location:44 → 427
    Nucleoside_tran; Nucleoside transporter

  3. NM_001268523.3 → NP_001255452.1  Equilibrative Nucleoside Transporter (ENT) Family [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255452.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1B6S0
    Conserved Domains (1) summary
    cl15430
    Location:1 → 139
    Nucleoside_tran; Nucleoside transporter

RNA

  1. NR_131591.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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