U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gtbp-1 Ras GTPase-activating protein-binding protein gtbp-1 [ Caenorhabditis elegans ]

Gene ID: 177880, updated on 2-Nov-2024

Summary

Official Symbol
gtbp-1
Official Full Name
Ras GTPase-activating protein-binding protein gtbp-1
Primary source
WormBase:WBGene00010677
Locus tag
CELE_K08F4.2
See related
AllianceGenome:WB:WBGene00010677
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in stress granule assembly. Located in cytoplasmic stress granule. Is expressed widely. Orthologous to human G3BP1 (G3BP stress granule assembly factor 1) and G3BP2 (G3BP stress granule assembly factor 2). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See gtbp-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (10126749..10128956, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Receptor L-domain domain-containing protein Neighboring gene AAA+ ATPase domain-containing protein Neighboring gene ncRNA Neighboring gene Translocon-associated protein subunit beta

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in stress granule assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intracellular organelle IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Ras GTPase-activating protein-binding protein gtbp-1
NP_501842.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10126749..10128956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069441.9NP_501842.2  Ras GTPase-activating protein-binding protein gtbp-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501842.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21351
    Conserved Domains (2) summary
    cd00780
    Location:33145
    NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
    cl17169
    Location:326404
    RRM_SF; RNA recognition motif (RRM) superfamily