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dhs-12 NAD(P)-binding protein [ Caenorhabditis elegans ]

Gene ID: 177888, updated on 2-Nov-2024

Summary

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Official Symbol
dhs-12
Official Full Name
NAD(P)-binding protein
Primary source
WormBase:WBGene00000975
Locus tag
CELE_K08F4.9
See related
AllianceGenome:WB:WBGene00000975
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable oxidoreductase activity. Predicted to be active in cytoplasm. Orthologous to human CBR1 (carbonyl reductase 1) and CBR3 (carbonyl reductase 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dhs-12 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (10145249..10146222)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene SH2 domain-containing protein Neighboring gene GPI transamidase component PIG-S

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Proteomic analysis of protein expression profiles during Caenorhabditis elegans development using two-dimensional difference gel electrophoresis. Tabuse Y, et al. Proteomics, 2005 Jul. PMID 15996007
  2. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
  3. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  4. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  5. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NAD(P)-binding protein
NP_501850.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10145249..10146222
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069449.8 → NP_501850.1  NAD(P)-binding protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501850.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EG13
    Conserved Domains (2) summary
    cd05325
    Location:6 → 254
    carb_red_sniffer_like_SDR_c; carbonyl reductase sniffer-like, classical (c) SDRs
    pfam00106
    Location:4 → 217
    adh_short; short chain dehydrogenase
Nucleotide Protein
Heading Accession and Version

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