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copg-1 Coatomer subunit gamma;putative coatomer subunit gamma [ Caenorhabditis elegans ]

Gene ID: 177891, updated on 2-Nov-2024

Summary

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Official Symbol
copg-1
Official Full Name
Coatomer subunit gamma;putative coatomer subunit gamma
Primary source
WormBase:WBGene00011775
Locus tag
CELE_T14G10.5
See related
AllianceGenome:WB:WBGene00011775
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable structural molecule activity. Predicted to be involved in Golgi vesicle transport; organelle transport along microtubule; and protein secretion. Predicted to be located in COPI-coated vesicle membrane and Golgi apparatus. Predicted to be part of COPI vesicle coat. Predicted to be active in Golgi membrane; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human COPG1 (COPI coat complex subunit gamma 1) and COPG2 (COPI coat complex subunit gamma 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See copg-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (10151947..10155639)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Tetraspanin-12 Neighboring gene ncRNA Neighboring gene Transthyretin-like family protein Neighboring gene Transthyretin-like family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. AP-1 Recruits SMAP-1/SMAPs to the trans-Golgi Network to Promote Sorting in Polarized Epithelia. Wang S, et al. Front Cell Dev Biol, 2021. PMID 34901019, Free PMC Article
  2. AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity. Ruiz M, et al. J Biol Chem, 2023 Jun. PMID 37164154, Free PMC Article
  3. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Zinovyeva AY, et al. Proc Natl Acad Sci U S A, 2015 Sep 22. PMID 26351692, Free PMC Article
  4. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
  5. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organelle transport along microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of COPI vesicle coat IEA
Inferred from Electronic Annotation
more info
  
located_in COPI-coated vesicle membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of membrane coat IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Coatomer subunit gamma;putative coatomer subunit gamma
NP_001040988.1
  • Confirmed by transcript evidence
NP_001040989.1
  • Confirmed by transcript evidence
NP_001255464.1
  • Confirmed by transcript evidence
NP_001293961.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10151947..10155639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268535.4 → NP_001255464.1  Coatomer subunit gamma [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255464.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F5GUA3
    Conserved Domains (5) summary
    COG5240
    Location:14 → 881
    SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
    pfam08752
    Location:624 → 767
    COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
    pfam12830
    Location:305 → 358
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam16381
    Location:769 → 884
    Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
    sd00044
    Location:408 → 433
    HEAT; HEAT repeat [structural motif]

  2. NM_001047524.5 → NP_001040989.1  Coatomer subunit gamma [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040989.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2XN02
    Conserved Domains (5) summary
    COG5240
    Location:14 → 879
    SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
    pfam08752
    Location:622 → 765
    COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
    pfam12830
    Location:303 → 356
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam16381
    Location:767 → 882
    Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
    sd00044
    Location:406 → 431
    HEAT; HEAT repeat [structural motif]

  3. NM_001047523.6 → NP_001040988.1  putative coatomer subunit gamma [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040988.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22498
    Conserved Domains (5) summary
    COG5240
    Location:1 → 866
    SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
    pfam08752
    Location:609 → 752
    COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
    pfam12830
    Location:290 → 343
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam16381
    Location:754 → 869
    Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
    sd00044
    Location:393 → 418
    HEAT; HEAT repeat [structural motif]

  4. NM_001307032.3 → NP_001293961.1  Coatomer subunit gamma [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293961.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A061ACR1
    Conserved Domains (5) summary
    COG5240
    Location:1 → 868
    SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
    pfam08752
    Location:611 → 754
    COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
    pfam12830
    Location:292 → 345
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam16381
    Location:756 → 871
    Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
    sd00044
    Location:395 → 420
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q22498.1

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