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gon-4 GON-4-like protein [ Caenorhabditis elegans ]

Gene ID: 177899, updated on 2-Nov-2024

Summary

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Official Symbol
gon-4
Official Full Name
GON-4-like protein
Primary source
WormBase:WBGene00001653
Locus tag
CELE_K04D7.5
See related
AllianceGenome:WB:WBGene00001653
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transcription coregulator activity. Involved in gonad development and positive regulation of cell division. Located in germ cell nucleus. Is expressed in germ line and gonad. Orthologous to human YY1AP1 (YY1 associated protein 1) and GON4L (gon-4 like). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gon-4 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
14
Sequence:
Chromosome: IV; NC_003282.8 (10197817..10202993)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Tyrosine-protein phosphatase 4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Serpentine receptor class gamma Neighboring gene ABC transporter domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The promotion of gonadal cell divisions by the Caenorhabditis elegans TRPM cation channel GON-2 is antagonized by GEM-4 copine. Church DL, et al. Genetics, 2003 Oct. PMID 14573470, Free PMC Article
  2. gon-4, a cell lineage regulator required for gonadogenesis in Caenorhabditis elegans. Friedman L, et al. Dev Biol, 2000 Dec 15. PMID 11112335
  3. The sys-1 and sys-3 genes cooperate with Wnt signaling to establish the proximal-distal axis of the Caenorhabditis elegans gonad. Siegfried KR, et al. Genetics, 2004 Jan. PMID 15020416, Free PMC Article
  4. Cyclin D regulation of a sexually dimorphic asymmetric cell division. Tilmann C, et al. Dev Cell, 2005 Oct. PMID 16198291, Free PMC Article
  5. Cell-Specific mRNA Profiling of the Caenorhabditis elegans Somatic Gonadal Precursor Cells Identifies Suites of Sex-Biased and Gonad-Enriched Transcripts. Kroetz MB, et al. G3 (Bethesda), 2015 Oct 23. PMID 26497144, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in gonad development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of cell division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in reproductive process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in germ cell nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GON-4-like protein
NP_001122786.1
  • Confirmed by transcript evidence
NP_501864.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10197817..10202993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069463.7 → NP_501864.2  GON-4-like protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501864.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21216

  2. NM_001129314.4 → NP_001122786.1  GON-4-like protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122786.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A5JYS9
Nucleotide Protein
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