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pfd-1 putative prefoldin subunit 1 [ Caenorhabditis elegans ]

Gene ID: 178021, updated on 2-Nov-2024

Summary

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Official Symbol
pfd-1
Official Full Name
putative prefoldin subunit 1
Primary source
WormBase:WBGene00007443
Locus tag
CELE_C08F8.1
See related
AllianceGenome:WB:WBGene00007443
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein folding chaperone and unfolded protein binding activity. Involved in gonad development. Located in cytoplasm. Is expressed in body wall musculature; excretory cell; intestine; pharynx; and vulval muscle. Orthologous to human PFDN1 (prefoldin subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pfd-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (11150113..11150930)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Phosphate carrier protein, mitochondrial Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase SUV3 homolog, mitochondrial Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans. Lundin VF, et al. Dev Biol, 2008 Jan 1. PMID 18062952
  2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein folding chaperone IBA
Inferred from Biological aspect of Ancestor
more info
  
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in gonad development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of prefoldin complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative prefoldin subunit 1
NP_001255540.1
  • Confirmed by transcript evidence
NP_001255541.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    11150113..11150930
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268611.4 → NP_001255540.1  putative prefoldin subunit 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255540.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    E9P871, Q17827
    Conserved Domains (1) summary
    pfam01920
    Location:11 → 114
    Prefoldin_2; Prefoldin subunit

  2. NM_001268612.4 → NP_001255541.1  putative prefoldin subunit 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255541.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17827
    Conserved Domains (1) summary
    pfam01920
    Location:1 → 77
    Prefoldin_2; Prefoldin subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q17827.1

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