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nhr-67 Nuclear hormone receptor family member nhr-67 [ Caenorhabditis elegans ]

Gene ID: 178024, updated on 2-Nov-2024

Summary

Official Symbol
nhr-67
Official Full Name
Nuclear hormone receptor family member nhr-67
Primary source
WormBase:WBGene00003657
Locus tag
CELE_C08F8.8
See related
AllianceGenome:WB:WBGene00003657
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including gonad morphogenesis; negative regulation of G1/S transition of mitotic cell cycle; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including excretory cell; gonad; head ganglion; neurons; and vulval cell. Orthologous to human NR2E1 (nuclear receptor subfamily 2 group E member 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See nhr-67 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
8
Sequence:
Chromosome: IV; NC_003282.8 (11169748..11174791)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene non-specific serine/threonine protein kinase Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RAP homolog (vertebrate Rap GTPase family) Neighboring gene Uncharacterized protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Nuclear hormone receptor family member nhr-67
NP_502094.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    11169748..11174791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069693.5NP_502094.1  Nuclear hormone receptor family member nhr-67 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502094.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XVV3
    UniProtKB/TrEMBL
    Q86PK2
    Conserved Domains (1) summary
    cl02596
    Location:13107
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers