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catp-8 putative manganese-transporting ATPase catp-8 [ Caenorhabditis elegans ]

Gene ID: 178070, updated on 2-Nov-2024

Summary

Official Symbol
catp-8
Official Full Name
putative manganese-transporting ATPase catp-8
Primary source
WormBase:WBGene00007514
Locus tag
CELE_C10C6.6
See related
AllianceGenome:WB:WBGene00007514
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity; P-type ion transporter activity; and protein transporter activity. Acts upstream of with a positive effect on dendrite morphogenesis. Located in endoplasmic reticulum. Is expressed in several structures, including body wall musculature; gonad; intestine; neurons; and pharynx. Orthologous to human ATP13A1 (ATPase 13A1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See catp-8 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
9
Sequence:
Chromosome: IV; NC_003282.8 (11473363..11479251, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Uncharacterized protein Neighboring gene ABC transporter domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene HTH cro/C1-type domain-containing protein Neighboring gene Non-structural maintenance of chromosomes element 4

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATPase-coupled monoatomic cation transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables P-type ion transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables P-type transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_positive_effect dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in monoatomic cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative manganese-transporting ATPase catp-8
NP_502165.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    11473363..11479251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069764.6NP_502165.2  putative manganese-transporting ATPase catp-8 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502165.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O02620, P90747
    Conserved Domains (4) summary
    COG4087
    Location:793842
    COG4087; Soluble P-type ATPase [General function prediction only]
    TIGR01657
    Location:371153
    P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
    pfam00122
    Location:251380
    E1-E2_ATPase; E1-E2 ATPase
    pfam13246
    Location:532613
    Cation_ATPase; Cation transport ATPase (P-type)