U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

sec-24.2 uncharacterized protein [ Caenorhabditis elegans ]

Gene ID: 178183, updated on 2-Nov-2024

Summary

Official Symbol
sec-24.2
Official Full Name
uncharacterized protein
Primary source
WormBase:WBGene00004756
Locus tag
CELE_ZC518.2
See related
AllianceGenome:WB:WBGene00004756
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to be located in ER to Golgi transport vesicle membrane; Golgi apparatus; and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Is expressed in DA neuron. Orthologous to several human genes including SEC24A (SEC24 homolog A, COPII coat complex component). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See sec-24.2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
11
Sequence:
Chromosome: IV; NC_003282.8 (12355600..12360792, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Bestrophin homolog;Bestrophin homolog 22 Neighboring gene Glutathione S-transferase Neighboring gene poly(A)-specific ribonuclease Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in COPII-coated vesicle cargo loading IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of COPII vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of COPII vesicle coat IEA
Inferred from Electronic Annotation
more info
 
located_in ER to Golgi transport vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum exit site IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein
NP_502354.2
  • Product from WormBase gene class sec;
    Confirmed by transcript evidence; yeast SEC homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12355600..12360792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069953.8NP_502354.2  uncharacterized protein CELE_ZC518.2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502354.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23368
    Conserved Domains (5) summary
    cd01479
    Location:403643
    Sec24-like; Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes ...
    pfam04810
    Location:330366
    zf-Sec23_Sec24; Sec23/Sec24 zinc finger
    pfam04815
    Location:742836
    Sec23_helical; Sec23/Sec24 helical domain
    pfam08033
    Location:644726
    Sec23_BS; Sec23/Sec24 beta-sandwich domain
    cl15697
    Location:860911
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains