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clec-186 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178238, updated on 2-Nov-2024

Summary

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Official Symbol
clec-186
Official Full Name
C-type lectin domain-containing protein
Primary source
WormBase:WBGene00014138
Locus tag
CELE_ZK896.7
See related
AllianceGenome:WB:WBGene00014138
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in innate immune response. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See clec-186 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (12866109..12869080)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene UDP-galactose transporter Neighboring gene Receptor-type guanylate cyclase gcy-18 Neighboring gene ncRNA Neighboring gene C-type lectin domain-containing protein Neighboring gene CUB-like domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Salmonella enterica serovar Paratyphi A-induced immune response in Caenorhabditis elegans depends on MAPK pathways and DAF-16. Ding AJ, et al. Front Immunol, 2023. PMID 37122724, Free PMC Article
  2. Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans. Schulenburg H, et al. Immunobiology, 2008. PMID 18406370
  3. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
  4. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
  5. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in innate immune response HEP PubMed 

General protein information

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Preferred Names
C-type lectin domain-containing protein
NP_502450.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12866109..12869080
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070049.5 → NP_502450.2  C-type lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502450.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O02343
    Conserved Domains (1) summary
    smart00034
    Location:31 → 144
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
Nucleotide Protein
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