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pqn-74 Chitin-binding type-2 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178294, updated on 2-Nov-2024

Summary

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Official Symbol
pqn-74
Official Full Name
Chitin-binding type-2 domain-containing protein
Primary source
WormBase:WBGene00004156
Locus tag
CELE_W02A2.3
See related
AllianceGenome:WB:WBGene00004156
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable chitin binding activity. Involved in endoplasmic reticulum unfolded protein response. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pqn-74 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (13329507..13331406, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Delta(12) fatty acid desaturase fat-2;Fatty acid desaturase Neighboring gene Fatty-acid and retinol-binding protein 1 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Viswanathan M, et al. Dev Cell, 2005 Nov. PMID 16256736
  2. A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target. Andachi Y. RNA, 2008 Nov. PMID 18824511, Free PMC Article
  3. A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. Urano F, et al. J Cell Biol, 2002 Aug 19. PMID 12186849, Free PMC Article
  4. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718
  5. A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins. Kamal M, et al. Elife, 2022 Oct 19. PMID 36259463, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response HEP PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Chitin-binding type-2 domain-containing protein
NP_001380173.1
  • Confirmed by transcript evidence
NP_502562.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13329507..13331406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070161.5 → NP_502562.1  Chitin-binding type-2 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502562.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XUB6
    Conserved Domains (1) summary
    smart00494
    Location:271 → 325
    ChtBD2; Chitin-binding domain type 2

  2. NM_001392428.1 → NP_001380173.1  Chitin-binding type-2 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A061AKS9
    Conserved Domains (1) summary
    smart00494
    Location:151 → 205
    ChtBD2; Chitin-binding domain type 2
Nucleotide Protein
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