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lin-66 GATA-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178354, updated on 2-Nov-2024

Summary

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Official Symbol
lin-66
Official Full Name
GATA-type domain-containing protein
Primary source
WormBase:WBGene00001562
Locus tag
CELE_B0513.1
See related
AllianceGenome:WB:WBGene00001562
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in negative regulation of gene expression and regulation of development, heterochronic. Located in cytoplasm. Is expressed in body wall musculature; hypodermis; intestine; neurons; and vulval muscle. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lin-66 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (13888079..13893986)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C. elegans LIN-66 mediates EIF-3/eIF3-dependent protein translation via a cold-shock domain. Blazie SM, et al. Life Sci Alliance, 2024 Sep. PMID 38886018, Free PMC Article
  2. Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans. Morita K, et al. EMBO J, 2006 Dec 13. PMID 17139256, Free PMC Article
  3. The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans. Huang X, et al. Development, 2011 May. PMID 21471153
  4. miRNAs give worms the time of their lives: small RNAs and temporal control in Caenorhabditis elegans. Resnick TD, et al. Dev Dyn, 2010 May. PMID 20232378, Free PMC Article
  5. Isolation of the interacting molecules with GEX-3 by a novel functional screening. Tsuboi D, et al. Biochem Biophys Res Commun, 2002 Apr 5. PMID 11922622

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. C. elegans LIN-66 mediates EIF-3/eIF3-dependent protein translation via a cold-shock domain.
    Title: C. elegans LIN-66 mediates EIF-3/eIF3-dependent protein translation via a cold-shock domain.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in negative regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of development, heterochronic IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of development, heterochronic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
GATA-type domain-containing protein
NP_001255767.1
  • Confirmed by transcript evidence
NP_001255768.1
  • Confirmed by transcript evidence
NP_001293994.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13888079..13893986
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001307065.3 → NP_001293994.1  GATA-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293994.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A061AL58

  2. NM_001268838.4 → NP_001255767.1  GATA-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255767.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62020

  3. NM_001268839.3 → NP_001255768.1  GATA-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255768.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3YT69
Nucleotide Protein
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