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semo-1 Methanethiol oxidase [ Caenorhabditis elegans ]

Gene ID: 178360, updated on 2-Nov-2024

Summary

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Official Symbol
semo-1
Official Full Name
Methanethiol oxidase
Primary source
WormBase:WBGene00012538
Locus tag
CELE_Y37A1B.5
See related
AllianceGenome:WB:WBGene00012538
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables methanethiol oxidase activity. Is expressed in hypodermis. Orthologous to human SELENBP1 (selenium binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See semo-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (14051200..14056717)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Transposase Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Selenium-Enriched E. coli Bacteria Mitigate the Age-Associated Degeneration of Cholinergic Neurons in C. elegans. Zytner P, et al. Antioxidants (Basel), 2024 Apr 20. PMID 38671939, Free PMC Article
  2. SEMO-1, a novel methanethiol oxidase in Caenorhabditis elegans, is a pro-aging factor conferring selective stress resistance. Philipp TM, et al. Biofactors, 2022 May. PMID 35316559
  3. Selenium-binding protein 1 (SELENBP1) is a copper-dependent thiol oxidase. Philipp TM, et al. Redox Biol, 2023 Sep. PMID 37437449, Free PMC Article
  4. A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. Köhnlein K, et al. Redox Biol, 2020 Jan. PMID 31557719, Free PMC Article
  5. Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans. Wang X, et al. EMBO J, 2022 Apr 19. PMID 35253240, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
    Title: A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables methanethiol oxidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables selenium binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Methanethiol oxidase
NP_001255777.1
  • Partially confirmed by transcript evidence
NP_001255778.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    14051200..14056717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268848.2 → NP_001255777.1  Methanethiol oxidase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255777.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XXF9
    Conserved Domains (1) summary
    pfam05694
    Location:9 → 471
    SBP56; 56kDa selenium binding protein (SBP56)

  2. NM_001268849.3 → NP_001255778.1  Methanethiol oxidase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255778.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3NQ99
    Conserved Domains (1) summary
    pfam05694
    Location:1 → 164
    SBP56; 56kDa selenium binding protein (SBP56)

RNA

  1. NR_131636.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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