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Y116A8C.24 Tyrosine-protein kinase [ Caenorhabditis elegans ]

Gene ID: 178481, updated on 2-Nov-2024

Summary

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Official Symbol
Y116A8C.24
Official Full Name
Tyrosine-protein kinase
Primary source
WormBase:WBGene00013801
Locus tag
CELE_Y116A8C.24
See related
AllianceGenome:WB:WBGene00013801
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; cell surface receptor protein tyrosine kinase signaling pathway; and innate immune response. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y116A8C.24 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (17068795..17070891, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables non-membrane spanning protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Tyrosine-protein kinase
NP_001255917.1
  • Confirmed by transcript evidence
NP_001255918.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    17068795..17070891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268989.3 → NP_001255918.1  Tyrosine-protein kinase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255918.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U2U8
    Conserved Domains (3) summary
    smart00219
    Location:181 → 446
    TyrKc; Tyrosine kinase, catalytic domain
    smart00252
    Location:70 → 155
    SH2; Src homology 2 domains
    cd00192
    Location:183 → 454
    PTKc; Catalytic domain of Protein Tyrosine Kinases

  2. NM_001268988.5 → NP_001255917.1  Tyrosine-protein kinase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255917.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H8ESG3
    Conserved Domains (3) summary
    smart00219
    Location:181 → 446
    TyrKc; Tyrosine kinase, catalytic domain
    smart00252
    Location:70 → 155
    SH2; Src homology 2 domains
    cd00192
    Location:183 → 454
    PTKc; Catalytic domain of Protein Tyrosine Kinases
Nucleotide Protein
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