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cgp-1 GTP-binding protein cgp-1;GTP_EFTU_D3 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178540, updated on 2-Nov-2024

Summary

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Official Symbol
cgp-1
Official Full Name
GTP-binding protein cgp-1;GTP_EFTU_D3 domain-containing protein
Primary source
WormBase:WBGene00000480
Locus tag
CELE_Y38C9A.2
See related
AllianceGenome:WB:WBGene00000480
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Orthologous to human GTPBP1 (GTP binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cgp-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (118202..122789, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein eS27 Neighboring gene Pry-1 Interacting and CABIN1 Domain containing Neighboring gene Zinc finger ZPR1-type domain-containing protein;Zinc finger protein ZPR1 homolog Neighboring gene C2H2-type domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
  2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  3. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
  4. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables translation elongation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
GTP-binding protein cgp-1;GTP_EFTU_D3 domain-containing protein
NP_001300232.1
  • Confirmed by transcript evidence
NP_001300233.1
  • Confirmed by transcript evidence
NP_503137.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    118202..122789 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070736.8 → NP_503137.1  GTP-binding protein cgp-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503137.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18905, Q9UAZ4
    Conserved Domains (4) summary
    cd04165
    Location:142 → 364
    GTPBP1_like; GTP binding protein 1 (GTPBP1)-like family includes GTPBP2
    COG5258
    Location:44 → 552
    GTPBP1; GTPase [General function prediction only]
    cd03694
    Location:373 → 459
    GTPBP_II; Domain II of the GTPBP family of GTP binding proteins
    cd03708
    Location:465 → 551
    GTPBP_III; Domain III of the GP-1 family of GTPases

  2. NM_001313303.3 → NP_001300232.1  GTP_EFTU_D3 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3ASE6
    Conserved Domains (2) summary
    cd03708
    Location:50 → 136
    GTPBP_III; Domain III of the GP-1 family of GTPases
    cl02787
    Location:1 → 44
    Translation_Factor_II_like; Domain II of Elongation factor Tu (EF-Tu)-like proteins

  3. NM_001313304.3 → NP_001300233.1  GTP_EFTU_D3 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AW00
    Conserved Domains (1) summary
    cd03708
    Location:11 → 97
    GTPBP_III; Domain III of the GP-1 family of GTPases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q18905.2

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