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dod-19 Downstream Of DAF-16 (regulated by DAF-16);GH131_N domain-containing protein;IgGFc_binding domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178564, updated on 2-Nov-2024

Summary

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Official Symbol
dod-19
Official Full Name
Downstream Of DAF-16 (regulated by DAF-16);GH131_N domain-containing protein;IgGFc_binding domain-containing protein
Primary source
WormBase:WBGene00022644
Locus tag
CELE_ZK6.10
See related
AllianceGenome:WB:WBGene00022644
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in innate immune response. Located in membrane raft. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dod-19 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (411782..414759, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene CUB_2 domain-containing protein Neighboring gene UNC93-like protein MFSD11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans. Honda Y, et al. PLoS One, 2011. PMID 21858156, Free PMC Article
  2. Identification and characterization of differentially expressed genes in Caenorhabditis elegans in response to pathogenic and nonpathogenic Stenotrophomonas maltophilia. Radeke LJ, et al. BMC Microbiol, 2020 Jun 19. PMID 32560629, Free PMC Article
  3. ADAR-mediated regulation of PQM-1 expression in neurons impacts gene expression throughout C. elegans and regulates survival from hypoxia. Mahapatra A, et al. PLoS Biol, 2023 Sep. PMID 37747897, Free PMC Article
  4. Salmonella enterica serovar Paratyphi A-induced immune response in Caenorhabditis elegans depends on MAPK pathways and DAF-16. Ding AJ, et al. Front Immunol, 2023. PMID 37122724, Free PMC Article
  5. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. Lee Y, et al. J Cell Biol, 2021 May 3. PMID 33666644, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in innate immune response HEP PubMed 
Component Evidence Code Pubs
located_in membrane raft HDA PubMed 

General protein information

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Preferred Names
Downstream Of DAF-16 (regulated by DAF-16);GH131_N domain-containing protein;IgGFc_binding domain-containing protein
NP_001300296.1
  • Confirmed by transcript evidence
NP_001300297.1
  • Product from WormBase gene class dod;
    Confirmed by transcript evidence
NP_503193.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    411782..414759 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070792.8 → NP_503193.1  IgGFc_binding domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503193.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O61874
    Conserved Domains (1) summary
    pfam03409
    Location:41 → 389
    Glycoprotein; Transmembrane glycoprotein

  2. NM_001313367.3 → NP_001300296.1  GH131_N domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AVF2
    Conserved Domains (1) summary
    pfam03409
    Location:4 → 236
    Glycoprotein; Transmembrane glycoprotein

  3. NM_001313368.3 → NP_001300297.1  Downstream Of DAF-16 (regulated by DAF-16) [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3ASK2
    Conserved Domains (1) summary
    pfam03409
    Location:9 → 40
    Glycoprotein; Transmembrane glycoprotein
Nucleotide Protein
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