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glb-33 GLOBIN domain-containing protein;G_PROTEIN_RECEP_F1_2 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178627, updated on 2-Nov-2024

Summary

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Official Symbol
glb-33
Official Full Name
GLOBIN domain-containing protein;G_PROTEIN_RECEP_F1_2 domain-containing protein
Primary source
WormBase:WBGene00022284
Locus tag
CELE_Y75B7AL.1
See related
AllianceGenome:WB:WBGene00022284
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in neurons and somatic nervous system. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See glb-33 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (1352126..1356594)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein amnionless Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C2 domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The effect of pH and nitrite on the haem pocket of GLB-33, a globin-coupled neuronal transmembrane receptor of Caenorhabditis elegans. Van Brempt N, et al. Biochim Biophys Acta Proteins Proteom, 2023 Jul 1. PMID 37004900
  2. A globin domain in a neuronal transmembrane receptor of Caenorhabditis elegans and Ascaris suum: molecular modeling and functional properties. Tilleman L, et al. J Biol Chem, 2015 Apr 17. PMID 25666609, Free PMC Article
  3. The Caenorhabditis globin gene family reveals extensive nematode-specific radiation and diversification. Hoogewijs D, et al. BMC Evol Biol, 2008 Oct 9. PMID 18844991, Free PMC Article
  4. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. Hoogewijs D, et al. BMC Genomics, 2007 Oct 4. PMID 17916248, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The effect of pH and nitrite on the haem pocket of GLB-33, a globin-coupled neuronal transmembrane receptor of Caenorhabditis elegans.
    Title: The effect of pH and nitrite on the haem pocket of GLB-33, a globin-coupled neuronal transmembrane receptor of Caenorhabditis elegans.
  2. The globin domain of GLB-33 may serve as a highly sensitive oxygen sensor and/or as a nitrite reductase.
    Title: A globin domain in a neuronal transmembrane receptor of Caenorhabditis elegans and Ascaris suum: molecular modeling and functional properties.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables neuropeptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxygen binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in neuropeptide signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
GLOBIN domain-containing protein;G_PROTEIN_RECEP_F1_2 domain-containing protein
NP_001300285.1
  • Confirmed by transcript evidence
NP_001300286.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    1352126..1356594
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001313356.3 → NP_001300285.1  G_PROTEIN_RECEP_F1_2 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AT43
    Conserved Domains (1) summary
    cd01040
    Location:386 → 531
    Mb_like; myoglobin_like; M family globin domain

  2. NM_001313357.3 → NP_001300286.1  GLOBIN domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AVE6
    Conserved Domains (1) summary
    cd01040
    Location:302 → 447
    Mb_like; myoglobin_like; M family globin domain
Nucleotide Protein
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