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lys-7 Lysozyme-like protein 7 [ Caenorhabditis elegans ]

Gene ID: 178772, updated on 2-Nov-2024

Summary

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Official Symbol
lys-7
Official Full Name
Lysozyme-like protein 7
Primary source
WormBase:WBGene00003096
Locus tag
CELE_C02A12.4
See related
AllianceGenome:WB:WBGene00003096
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in defense response to other organism. Is expressed in head neurons; intestine; and rectal gland cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lys-7 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (3481432..3482600, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class BC (Class B-like) Neighboring gene Serpentine Receptor, class BC (Class B-like) Neighboring gene Serpentine Receptor, class BC (Class B-like) Neighboring gene Serpentine Receptor, class BC (Class B-like)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Black sea cucumber (Holothuria atra Jaeger, 1833) rescues Pseudomonas aeruginosa-infected Caenorhabditis elegans via reduction of pathogen virulence factors and enhancement of host immunity. Lee WT, et al. Food Funct, 2019 Sep 1. PMID 31453615
  2. A Marine Actinomycete Rescues Caenorhabditis elegans from Pseudomonas aeruginosa Infection through Restitution of Lysozyme 7. Fatin SN, et al. Front Microbiol, 2017. PMID 29201023, Free PMC Article
  3. Swietenia macrophylla extract promotes the ability of Caenorhabditis elegans to survive Pseudomonas aeruginosa infection. Dharmalingam K, et al. J Ethnopharmacol, 2012 Jan 31. PMID 22193176
  4. Establishment of a Caenorhabditis elegans infection model for Vibrio alginolyticus. Durai S, et al. J Basic Microbiol, 2011 Jun. PMID 21298688
  5. Chronic exposure to di(2-ethylhexyl) phthalate (DEHP) weakens innate immunity and leads to immunosenescence in C. elegans. Yen PL, et al. Environ Toxicol Pharmacol, 2023 Mar. PMID 36690191

See all (66) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in defense response to Gram-positive bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in defense response to fungus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
  
involved_in innate immune response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to stress IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Lysozyme-like protein 7
NP_503972.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    3481432..3482600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071571.9 → NP_503972.1  Lysozyme-like protein 7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503972.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O16202
    Conserved Domains (1) summary
    cd06416
    Location:54 → 256
    GH25_Lys1-like; Lys-1 is a lysozyme encoded by the Caenorhabditis elegans lys-1 gene. This gene is one of a several lysozyme genes upregulated upon infection by the Gram-negative bacterial pathogen Serratia marcescens. Lys-1 contains a glycosyl hydrolase family 25 ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O16202.1

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