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exc-15 NADP-dependent oxidoreductase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178844, updated on 2-Nov-2024

Summary

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Official Symbol
exc-15
Official Full Name
NADP-dependent oxidoreductase domain-containing protein
Primary source
WormBase:WBGene00020369
Locus tag
CELE_T08H10.1
See related
AllianceGenome:WB:WBGene00020369
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable aldose reductase (NADPH) activity. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See exc-15 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (4483459..4486543)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Homeobox domain-containing protein;Homeobox protein unc-62 Neighboring gene Transmembrane protein Neighboring gene Son of sevenless homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Establishing a blueprint for CED-3-dependent killing through identification of multiple substrates for this protease. Taylor RC, et al. J Biol Chem, 2007 May 18. PMID 17371877
  2. Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements. Maroilley T, et al. Genome Res, 2023 Jan. PMID 36617680, Free PMC Article
  3. AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity. Ruiz M, et al. J Biol Chem, 2023 Jun. PMID 37164154, Free PMC Article
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables aldose reductase (NADPH) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NADP-dependent oxidoreductase domain-containing protein
NP_001367925.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    4483459..4486543
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001380633.2 → NP_001367925.1  NADP-dependent oxidoreductase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22352
    Conserved Domains (1) summary
    cd19154
    Location:3 → 306
    AKR_AKR1G1_CeAKR; Caenorhabditis elegans aldo-keto reductase (CeAKR) and similar proteins
Nucleotide Protein
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