U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nhr-47 Nuclear hormone receptor family member nhr-47 [ Caenorhabditis elegans ]

Gene ID: 178933, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
nhr-47
Official Full Name
Nuclear hormone receptor family member nhr-47
Primary source
WormBase:WBGene00003637
Locus tag
CELE_C24G6.4
See related
AllianceGenome:WB:WBGene00003637
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in intestine; neurons; pharynx; spermatheca; and ventral nerve cord. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See nhr-47 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (5505253..5509956)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DNaJ domain (prokaryotic heat shock protein) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Amine oxidase domain-containing protein Neighboring gene MMS19 nucleotide excision repair protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility. Charlesworth AG, et al. Nucleic Acids Res, 2021 Sep 7. PMID 34329465, Free PMC Article
  2. CSR-1 RNAi pathway positively regulates histone expression in C. elegans. Avgousti DC, et al. EMBO J, 2012 Oct 3. PMID 22863779, Free PMC Article
  3. Regulation of heterochromatin assembly on unpaired chromosomes during Caenorhabditis elegans meiosis by components of a small RNA-mediated pathway. She X, et al. PLoS Genet, 2009 Aug. PMID 19714217, Free PMC Article
  4. Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs. Kudron M, et al. Genome Biol, 2013 Jan 23. PMID 23347407, Free PMC Article
  5. Transgenerational Response of Germline Nuclear Hormone Receptor Genes to Nanoplastics at Predicted Environmental Doses in Caenorhabditis elegans. Liu Z, et al. Toxics, 2024 Jun 7. PMID 38922100, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Nuclear hormone receptor family member nhr-47
NP_504455.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    5505253..5509956
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072054.6 → NP_504455.1  Nuclear hormone receptor family member nhr-47 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504455.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O76382, Q17370
    Conserved Domains (2) summary
    cd06960
    Location:11 → 86
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
    smart00430
    Location:423 → 523
    HOLI; Ligand binding domain of hormone receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q17370.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous