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C04E6.5 ubiquitinyl hydrolase 1 [ Caenorhabditis elegans ]

Gene ID: 178977, updated on 2-Nov-2024

Summary

Official Symbol
C04E6.5
Official Full Name
ubiquitinyl hydrolase 1
Primary source
WormBase:WBGene00015422
Locus tag
CELE_C04E6.5
See related
AllianceGenome:WB:WBGene00015422
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in ERAD pathway and regulation of protein stability. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See C04E6.5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
10
Sequence:
Chromosome: V; NC_003283.11 (5902133..5904843)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene HAD family phosphatase Neighboring gene Ground-like domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Glycoprotein 120

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of protein stability IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ubiquitinyl hydrolase 1
NP_504537.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    5902133..5904843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072136.4NP_504537.1  ubiquitinyl hydrolase 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504537.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01467
    Conserved Domains (1) summary
    cd02673
    Location:146513
    Peptidase_C19Q; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...