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atp-4 ATP synthase-coupling factor 6, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 179025, updated on 2-Nov-2024

Summary

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Official Symbol
atp-4
Official Full Name
ATP synthase-coupling factor 6, mitochondrial
Primary source
WormBase:WBGene00020275
Locus tag
CELE_T05H4.12
See related
AllianceGenome:WB:WBGene00020275
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable proton transmembrane transporter activity. Predicted to be involved in proton motive force-driven ATP synthesis and proton transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of proton-transporting ATP synthase complex. Orthologous to human ATP5PF (ATP synthase peripheral stalk subunit F6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See atp-4 in Genome Data Viewer
Location:
chromosome: V
Exon count:
2
Sequence:
Chromosome: V; NC_003283.11 (6426246..6427112, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Nucleolar pre-ribosomal-associated protein 1 C-terminal domain-containing protein Neighboring gene tRNA Neighboring gene DUF4706 domain-containing protein Neighboring gene Aldehyde dehydrogenase Neighboring gene Gastrulation defective protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bacterial peptidoglycan muropeptides benefit mitochondrial homeostasis and animal physiology by acting as ATP synthase agonists. Tian D, et al. Dev Cell, 2022 Feb 7. PMID 35045336, Free PMC Article
  2. The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging. Angeli S, et al. Elife, 2021 Sep 1. PMID 34467850, Free PMC Article
  3. RNAi screening for modulators of an osmo-sensitive gene response to extracellular matrix damage reveals negative feedback and interactions with translation inhibition. Chandler LM, et al. PLoS One, 2023. PMID 37155688, Free PMC Article
  4. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. Hansen M, et al. PLoS Genet, 2005 Jul. PMID 16103914, Free PMC Article
  5. The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling. Rüegger S, et al. Nucleic Acids Res, 2015 Mar 31. PMID 25753661, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of proton-transporting ATP synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP synthase-coupling factor 6, mitochondrial
NP_001379991.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6426246..6427112 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392530.1 → NP_001379991.1  ATP synthase-coupling factor 6, mitochondrial [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16517
    Conserved Domains (1) summary
    pfam05511
    Location:3 → 62
    ATP-synt_F6; Mitochondrial ATP synthase coupling factor 6
Nucleotide Protein
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