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soap-1 HEAT repeat-containing protein 5B [ Caenorhabditis elegans ]

Gene ID: 179109, updated on 2-Nov-2024

Summary

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Official Symbol
soap-1
Official Full Name
HEAT repeat-containing protein 5B
Primary source
WormBase:WBGene00015743
Locus tag
CELE_C13F10.4
See related
AllianceGenome:WB:WBGene00015743
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in apical protein localization. Predicted to be located in cytosol. Predicted to be active in endocytic vesicle. Is expressed in intestine; nervous system; and reproductive system. Orthologous to human HEATR5A (HEAT repeat containing 5A) and HEATR5B (HEAT repeat containing 5B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See soap-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
12
Sequence:
Chromosome: V; NC_003283.11 (7205626..7214902, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Protein CNPPD1 Neighboring gene Protein kinase domain-containing protein Neighboring gene SAYSvFN domain-containing protein Neighboring gene FTH domain-containing protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Control of E-cadherin apical localisation and morphogenesis by a SOAP-1/AP-1/clathrin pathway in C. elegans epidermal cells. Gillard G, et al. Development, 2015 May 1. PMID 25858456
  2. Caenorhabditis elegans mutant allele identification by whole-genome sequencing. Sarin S, et al. Nat Methods, 2008 Oct. PMID 18677319, Free PMC Article
  3. High-throughput in vivo analysis of gene expression in Caenorhabditis elegans. Hunt-Newbury R, et al. PLoS Biol, 2007 Sep. PMID 17850180, Free PMC Article
  4. Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements. Maroilley T, et al. Genome Res, 2023 Jan. PMID 36617680, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SOAP-1 controls AP-1 localization and induces a basolateral localisation of E-cad without affecting the apico-basal diffusion barrier.
    Title: Control of E-cadherin apical localisation and morphogenesis by a SOAP-1/AP-1/clathrin pathway in C. elegans epidermal cells.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in apical protein localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
is_active_in endocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
HEAT repeat-containing protein 5B
NP_504828.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    7205626..7214902 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072427.6 → NP_504828.1  HEAT repeat-containing protein 5B [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504828.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01485
Nucleotide Protein
Heading Accession and Version

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