uvs-1 UV-stimulated scaffold protein A homolog [Caenorhabditis elegans] - Gene

Summary

Official Symbol: uvs-1
Official Full Name: UV-stimulated scaffold protein A homolog
Primary source: WormBase:WBGene00022812
Locus tag: CELE_ZK742.2
See related: AllianceGenome:WB:WBGene00022812
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA polymerase II complex binding activity. Involved in response to UV and transcription-coupled nucleotide-excision repair. Predicted to be active in chromosome. Human ortholog(s) of this gene implicated in UV-sensitive syndrome. Orthologous to human UVSSA (UV stimulated scaffold protein A). [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

functional homolog of the human UVSSA gene in the nematode Caenorhabditis elegans
Title: A C. elegans homolog for the UV-hypersensitivity syndrome disease gene UVSSA.

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Function	Evidence Code	Pubs
enables RNA polymerase II complex binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in DNA repair	IEA Inferred from Electronic Annotation more info
involved_in response to UV	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to UV	IEA Inferred from Electronic Annotation more info
involved_in response to UV	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription-coupled nucleotide-excision repair	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription-coupled nucleotide-excision repair	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in chromosome	IBA Inferred from Biological aspect of Ancestor more info
located_in chromosome	IEA Inferred from Electronic Annotation more info

NP_505012.2

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