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ech-3 Enoyl-CoA hydratase [ Caenorhabditis elegans ]

Gene ID: 179180, updated on 2-Nov-2024

Summary

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Official Symbol
ech-3
Official Full Name
Enoyl-CoA hydratase
Primary source
WormBase:WBGene00001152
Locus tag
CELE_F43H9.1
See related
AllianceGenome:WB:WBGene00001152
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in IRE1-mediated unfolded protein response. Is expressed in intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ech-3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (8022217..8023317)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene BSD domain-containing protein Neighboring gene Serine palmitoyltransferase 2 Neighboring gene Polymerase nucleotidyl transferase domain-containing protein Neighboring gene ncRNA Neighboring gene Glycine N-acyltransferase-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Exposure to 6-PPD quinone enhances lipid accumulation through activating metabolic sensors of SBP-1 and MDT-15 in Caenorhabditis elegans. Wang Y, et al. Environ Pollut, 2023 Sep 15. PMID 37307863
  2. Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms. Srinivasan S, et al. Cell Metab, 2008 Jun. PMID 18522834, Free PMC Article
  3. Systems-level transcriptional regulation of Caenorhabditis elegans metabolism. Nanda S, et al. Mol Syst Biol, 2023 May 9. PMID 36942755, Free PMC Article
  4. Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans. Brock TJ, et al. Genetics, 2007 Jun. PMID 17435249, Free PMC Article
  5. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Van Gilst MR, et al. Proc Natl Acad Sci U S A, 2005 Sep 20. PMID 16157872, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in IRE1-mediated unfolded protein response HEP PubMed 

General protein information

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Preferred Names
Enoyl-CoA hydratase
NP_001309646.1
  • Confirmed by transcript evidence
NP_505066.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    8022217..8023317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072665.7 → NP_505066.1  Enoyl-CoA hydratase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505066.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20376
    Conserved Domains (1) summary
    cl23717
    Location:7 → 247
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

  2. NM_001322576.3 → NP_001309646.1  Enoyl-CoA hydratase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MCK1
    Conserved Domains (1) summary
    cl23717
    Location:4 → 198
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
Nucleotide Protein
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