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grd-5 Ground-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179244, updated on 2-Nov-2024

Summary

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Official Symbol
grd-5
Official Full Name
Ground-like domain-containing protein
Primary source
WormBase:WBGene00001694
Locus tag
CELE_F41E6.2
See related
AllianceGenome:WB:WBGene00001694
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable signaling receptor binding activity. Involved in embryo development. Predicted to be located in extracellular region. Is expressed in anterior arcade cell; hypodermis; pharyngeal neurons; and vulval cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See grd-5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
2
Sequence:
Chromosome: V; NC_003283.11 (8619032..8619870)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Intrinsically Disordered Protein, class C Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Maeda I, et al. Curr Biol, 2001 Feb 6. PMID 11231151
  2. Warthog and groundhog, novel families related to hedgehog. Bürglin TR. Curr Biol, 1996 Sep 1. PMID 8805384
  3. Caenorhabditis elegans has scores of hedgehog-related genes: sequence and expression analysis. Aspöck G, et al. Genome Res, 1999 Oct. PMID 10523520
  4. Comprehensive analysis of gene expression patterns of hedgehog-related genes. Hao L, et al. BMC Genomics, 2006 Oct 31. PMID 17076889, Free PMC Article
  5. The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans. Zugasti O, et al. Genome Res, 2005 Oct. PMID 16204193, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables signaling receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell communication ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Ground-like domain-containing protein
NP_505223.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    8619032..8619870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072822.6 → NP_505223.1  Ground-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505223.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16462
    Conserved Domains (1) summary
    pfam04155
    Location:27 → 100
    Ground-like; Ground-like domain
Nucleotide Protein
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