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cht-5 Glycoside hydrolase family 19 catalytic domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179407, updated on 2-Nov-2024

Summary

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Official Symbol
cht-5
Official Full Name
Glycoside hydrolase family 19 catalytic domain-containing protein
Primary source
WormBase:WBGene00007425
Locus tag
CELE_C08B6.4
See related
AllianceGenome:WB:WBGene00007425
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable chitinase activity. Predicted to be involved in cell wall macromolecule catabolic process and chitin catabolic process. Is expressed in amphid neurons and hypodermis. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cht-5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (10114629..10117413)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DUF19 domain-containing protein;PIR Superfamily Protein Neighboring gene Uncharacterized protein Neighboring gene Glycosyltransferase family 92 protein Neighboring gene ncRNA Neighboring gene PBPe domain-containing protein Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Secretion of a novel developmentally regulated chitinase (family 19 glycosyl hydrolase) into the perivitelline fluid of the parasitic nematode, Ascaris suum. Geng J, et al. Mol Biochem Parasitol, 2002 Sep-Oct. PMID 12387846
  2. A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins. Kamal M, et al. Elife, 2022 Oct 19. PMID 36259463, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables chitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell wall macromolecule catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in chitin catabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Glycoside hydrolase family 19 catalytic domain-containing protein
NP_001023635.1
  • Confirmed by transcript evidence
NP_001366780.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10114629..10117413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001028464.3 → NP_001023635.1  Glycoside hydrolase family 19 catalytic domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023635.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q65ZB0
    Conserved Domains (2) summary
    cd00325
    Location:101 → 398
    chitinase_glyco_hydro_19; Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some ...
    pfam00182
    Location:101 → 391
    Glyco_hydro_19; Chitinase class I

  2. NM_001380734.2 → NP_001366780.1  Glycoside hydrolase family 19 catalytic domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17816
    Conserved Domains (1) summary
    cd00325
    Location:64 → 361
    chitinase_GH19; Glycoside hydrolase family 19, chitinase domain
Nucleotide Protein
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