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zhit-3 HIT-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179420, updated on 2-Nov-2024

Summary

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Official Symbol
zhit-3
Official Full Name
HIT-type domain-containing protein
Primary source
WormBase:WBGene00006489
Locus tag
CELE_ZK856.9
See related
AllianceGenome:WB:WBGene00006489
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in box C/D snoRNP assembly; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and snoRNA localization. Located in nucleus. Is expressed in germ line and hypodermis. Orthologous to human ZNHIT6 (zinc finger HIT-type containing 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See zhit-3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (10210444..10212127, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase III subunit RPC8 Neighboring gene TPR_REGION domain-containing protein Neighboring gene Hypersensitive to pore-forming toxin protein 40 Neighboring gene Serpentine Receptor, class BC (Class B-like);Serpentine Receptor, class U Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans. Evans KS, et al. PLoS Genet, 2020 Nov. PMID 33175833, Free PMC Article
  2. Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction. Szewczyk NJ, et al. J Exp Biol, 2006 Oct. PMID 17023606
  3. Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans. Cui M, et al. PLoS Genet, 2006 May. PMID 16710447, Free PMC Article
  4. An actin-based viscoplastic lock ensures progressive body-axis elongation. Lardennois A, et al. Nature, 2019 Sep. PMID 31462781, Free PMC Article
  5. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in box C/D snoRNP assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in snoRNA localization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of pre-snoRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
HIT-type domain-containing protein
NP_505627.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10210444..10212127 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073226.5 → NP_505627.1  HIT-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505627.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23644
    Conserved Domains (1) summary
    pfam04438
    Location:81 → 110
    zf-HIT; HIT zinc finger
Nucleotide Protein
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